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Potential of platinum-resensitization by Wnt signaling modulators as treatment approach for epithelial ovarian cancer

PURPOSE: Canonical Wnt/ β-catenin pathway is one mechanism being activated in platinum-resistant epithelial ovarian cancer (EOC). Detecting potential targets for Wnt pathway modulation as a putative future therapeutic approach was the aim of this study. METHODS: Biological effects of different Wnt m...

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Detalles Bibliográficos
Autores principales: Kaltofen, Till, Preinfalk, Valentina, Schwertler, Stephanie, Fraungruber, Patricia, Heidegger, Helene, Vilsmaier, Theresa, Vattai, Aurelia, Czogalla, Bastian, Mayr, Doris, Mahner, Sven, Jeschke, Udo, Trillsch, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467966/
https://www.ncbi.nlm.nih.gov/pubmed/32681294
http://dx.doi.org/10.1007/s00432-020-03317-4