Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

Genome-wide association studies have identified genetic variation contributing to complex disease risk. However, assigning causal genes and mechanisms has been more challenging because disease-associated variants are often found in distal regulatory regions with cell-type specific behaviours. Here,...

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Detalles Bibliográficos
Autores principales: Yang, Jing, McGovern, Amanda, Martin, Paul, Duffus, Kate, Ge, Xiangyu, Zarrineh, Peyman, Morris, Andrew P., Adamson, Antony, Fraser, Peter, Rattray, Magnus, Eyre, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468106/
https://www.ncbi.nlm.nih.gov/pubmed/32879318
http://dx.doi.org/10.1038/s41467-020-18180-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468106/
https://www.ncbi.nlm.nih.gov/pubmed/32879318
http://dx.doi.org/10.1038/s41467-020-18180-7

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