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Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis
Genome-wide association studies have identified genetic variation contributing to complex disease risk. However, assigning causal genes and mechanisms has been more challenging because disease-associated variants are often found in distal regulatory regions with cell-type specific behaviours. Here,...
Autores principales: | Yang, Jing, McGovern, Amanda, Martin, Paul, Duffus, Kate, Ge, Xiangyu, Zarrineh, Peyman, Morris, Andrew P., Adamson, Antony, Fraser, Peter, Rattray, Magnus, Eyre, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468106/ https://www.ncbi.nlm.nih.gov/pubmed/32879318 http://dx.doi.org/10.1038/s41467-020-18180-7 |
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