PLCɛ maintains the functionality of AR signaling in prostate cancer via an autophagy-dependent mechanism

Androgen receptor (AR) signaling is a major driver of prostate cancer (CaP). Although most therapies targeting AR are initially effective in CaP patients, drug resistance is inevitable, mainly because of the inappropriate re-activation of AR pathway. However, the underlying mechanisms remain largely...

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Detalles Bibliográficos
Autores principales: Quan, Zhen, Li, Ting, Xia, Yang, Liu, Jiayu, Du, Zhongbo, Luo, Chunli, He, Yunfeng, Wu, Xiaohou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468107/
https://www.ncbi.nlm.nih.gov/pubmed/32879302
http://dx.doi.org/10.1038/s41419-020-02917-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468107/
https://www.ncbi.nlm.nih.gov/pubmed/32879302
http://dx.doi.org/10.1038/s41419-020-02917-9

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