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Metabolic alterations in Parkinson’s disease astrocytes

In Parkinson`s disease (PD), the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta is associated with Lewy bodies arising from the accumulation of alpha-synuclein protein which leads ultimately to movement impairment. While PD has been considered a disease of the DA neurons, a...

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Detalles Bibliográficos
Autores principales: Sonninen, Tuuli-Maria, Hämäläinen, Riikka H., Koskuvi, Marja, Oksanen, Minna, Shakirzyanova, Anastasia, Wojciechowski, Sara, Puttonen, Katja, Naumenko, Nikolay, Goldsteins, Gundars, Laham-Karam, Nihay, Lehtonen, Marko, Tavi, Pasi, Koistinaho, Jari, Lehtonen, Šárka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468111/
https://www.ncbi.nlm.nih.gov/pubmed/32879386
http://dx.doi.org/10.1038/s41598-020-71329-8