The short isoform of extended synaptotagmin-2 controls Ca(2+) dynamics in T cells via interaction with STIM1

Ca(2+) release-activated Ca(2+) (CRAC) channels elevate cytoplasmic Ca(2+) concentration, which is essential for T cell activation, differentiation and effector functions. T cell receptor stimulation induces depletion of the endoplasmic reticulum (ER) Ca(2+) stores, which is sensed by stromal intera...

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Detalles Bibliográficos
Autores principales: Woo, Jin Seok, Sun, Zuoming, Srikanth, Sonal, Gwack, Yousang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468131/
https://www.ncbi.nlm.nih.gov/pubmed/32879390
http://dx.doi.org/10.1038/s41598-020-71489-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468131/
https://www.ncbi.nlm.nih.gov/pubmed/32879390
http://dx.doi.org/10.1038/s41598-020-71489-7

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