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The short isoform of extended synaptotagmin-2 controls Ca(2+) dynamics in T cells via interaction with STIM1
Ca(2+) release-activated Ca(2+) (CRAC) channels elevate cytoplasmic Ca(2+) concentration, which is essential for T cell activation, differentiation and effector functions. T cell receptor stimulation induces depletion of the endoplasmic reticulum (ER) Ca(2+) stores, which is sensed by stromal intera...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468131/ https://www.ncbi.nlm.nih.gov/pubmed/32879390 http://dx.doi.org/10.1038/s41598-020-71489-7 |