In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody leads to behavioral abnormalities resembling autism spectrum disorder in male mice

The concept that exposure in utero to maternal anti-brain antibodies contributes to the development of autism spectrum disorders (ASD) has been entertained for over a decade. We determined that antibodies targeting Caspr2 are present at high frequency in mothers with brain-reactive serology and a ch...

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Detalles Bibliográficos
Autores principales: Bagnall-Moreau, Ciara, Huerta, Patricio T., Comoletti, Davide, La-Bella, Andrea, Berlin, Roseann, Zhao, Chunfang, Volpe, Bruce T., Diamond, Betty, Brimberg, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468145/
https://www.ncbi.nlm.nih.gov/pubmed/32879327
http://dx.doi.org/10.1038/s41598-020-71201-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468145/
https://www.ncbi.nlm.nih.gov/pubmed/32879327
http://dx.doi.org/10.1038/s41598-020-71201-9

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