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VEGF-A splice variants bind VEGFRs with differential affinities

Vascular endothelial growth factor A (VEGF-A) and its binding to VEGFRs is an important angiogenesis regulator, especially the earliest-known isoform, VEGF-A(165a). Yet several additional splice variants play prominent roles in regulating angiogenesis in health and in vascular disease, including VEG...

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Detalles Bibliográficos
Autores principales: Mamer, Spencer B., Wittenkeller, Ashley, Imoukhuede, P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468149/
https://www.ncbi.nlm.nih.gov/pubmed/32879419
http://dx.doi.org/10.1038/s41598-020-71484-y