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Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy

Epithelial–mesenchymal transition (EMT) of renal tubular epithelial cells is one of the potential mechanisms of renal fibrosis, which promotes the development of diabetic nephropathy (DN). However, the molecular mechanisms of EMT remain largely unknown. Tuberous sclerosis proteins TSC1 and TSC2 are...

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Detalles Bibliográficos
Autores principales: Lu, Qian, Chen, Yi-bing, Yang, Hao, Wang, Wen-wen, Li, Cheng-cheng, Wang, Lei, Wang, Jin, Du, Lei, Yin, Xiao-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468253/
https://www.ncbi.nlm.nih.gov/pubmed/31235817
http://dx.doi.org/10.1038/s41401-019-0244-6