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Inactivation of TSC1 promotes epithelial-mesenchymal transition of renal tubular epithelial cells in mouse diabetic nephropathy
Epithelial–mesenchymal transition (EMT) of renal tubular epithelial cells is one of the potential mechanisms of renal fibrosis, which promotes the development of diabetic nephropathy (DN). However, the molecular mechanisms of EMT remain largely unknown. Tuberous sclerosis proteins TSC1 and TSC2 are...
Autores principales: | Lu, Qian, Chen, Yi-bing, Yang, Hao, Wang, Wen-wen, Li, Cheng-cheng, Wang, Lei, Wang, Jin, Du, Lei, Yin, Xiao-xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468253/ https://www.ncbi.nlm.nih.gov/pubmed/31235817 http://dx.doi.org/10.1038/s41401-019-0244-6 |
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