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Ca(2+)-activated KCa3.1 potassium channels contribute to the slow afterhyperpolarization in L5 neocortical pyramidal neurons

Layer 5 neocortical pyramidal neurons are known to display slow Ca(2+)-dependent afterhyperpolarization (sAHP) after bursts of spikes, which is similar to the sAHP in CA1 hippocampal cells. However, the mechanisms of sAHP in the neocortex remain poorly understood. Here, we identified the Ca(2+)-gate...

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Detalles Bibliográficos
Autores principales: Roshchin, M. V., Ierusalimsky, V. N., Balaban, P. M., Nikitin, E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468258/
https://www.ncbi.nlm.nih.gov/pubmed/32879404
http://dx.doi.org/10.1038/s41598-020-71415-x