A thienopyridine, CB-20, exerts diuretic activity by inhibiting urea transporters

Urea transporters (UTs) are transmembrane proteins selectively permeable to urea and play an important role in urine concentration. UT-knockout mice exhibit the urea-selective urine-concentrating defect, without affecting electrolyte balance, suggesting that UT-B inhibitors have the potential to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Min, Zhao, Yan, Zhang, Shun, Xu, Yue, Wang, Shu-yuan, Li, Bo-wen, Ran, Jian-hua, Li, Run-tao, Yang, Bao-xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468274/
https://www.ncbi.nlm.nih.gov/pubmed/31213671
http://dx.doi.org/10.1038/s41401-019-0245-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468274/
https://www.ncbi.nlm.nih.gov/pubmed/31213671
http://dx.doi.org/10.1038/s41401-019-0245-5

Ejemplares similares