Cargando…
A thienopyridine, CB-20, exerts diuretic activity by inhibiting urea transporters
Urea transporters (UTs) are transmembrane proteins selectively permeable to urea and play an important role in urine concentration. UT-knockout mice exhibit the urea-selective urine-concentrating defect, without affecting electrolyte balance, suggesting that UT-B inhibitors have the potential to be...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468274/ https://www.ncbi.nlm.nih.gov/pubmed/31213671 http://dx.doi.org/10.1038/s41401-019-0245-5 |