Direct formalin fixation induces widespread transcriptomic effects in archival tissue samples

Sequencing technologies now provide unprecedented access to genomic information in archival formalin-fixed paraffin-embedded (FFPE) tissue samples. However, little is known about artifacts induced during formalin fixation, which could bias results. Here we evaluated global changes in RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Wehmas, Leah C., Hester, Susan D., Wood, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468282/
https://www.ncbi.nlm.nih.gov/pubmed/32879405
http://dx.doi.org/10.1038/s41598-020-71521-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468282/
https://www.ncbi.nlm.nih.gov/pubmed/32879405
http://dx.doi.org/10.1038/s41598-020-71521-w

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