Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors

As with many G protein-coupled receptors (GPCRs), the signalling pathways regulated by the dopamine D1 receptor (D1R) are dynamic, cell type-specific, and can change in the face of disease or drug exposures. In striatal neurons, the D1R activates cAMP/protein kinase A (PKA) signalling. However, in P...

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Detalles Bibliográficos
Autores principales: Jones-Tabah, Jace, Mohammad, Hanan, Hadj-Youssef, Shadi, Kim, Lucy E. H., Martin, Ryan D., Benaliouad, Faïza, Tanny, Jason C., Clarke, Paul B. S., Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468292/
https://www.ncbi.nlm.nih.gov/pubmed/32879346
http://dx.doi.org/10.1038/s41598-020-71121-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468292/
https://www.ncbi.nlm.nih.gov/pubmed/32879346
http://dx.doi.org/10.1038/s41598-020-71121-8

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