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Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence

Midbrain dopaminergic (DA) neurons are governed by an endogenous cholinergic system, originated in the mesopontine nuclei. Nicotine hijacks nicotinic acetylcholine receptors (nAChRs) and interferes with physiological function of the cholinergic system. In this review, we describe the anatomical orga...

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Detalles Bibliográficos
Autores principales: Xiao, Cheng, Zhou, Chun-yi, Jiang, Jin-hong, Yin, Cui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468330/
https://www.ncbi.nlm.nih.gov/pubmed/31554960
http://dx.doi.org/10.1038/s41401-019-0299-4