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Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence
Midbrain dopaminergic (DA) neurons are governed by an endogenous cholinergic system, originated in the mesopontine nuclei. Nicotine hijacks nicotinic acetylcholine receptors (nAChRs) and interferes with physiological function of the cholinergic system. In this review, we describe the anatomical orga...
Autores principales: | Xiao, Cheng, Zhou, Chun-yi, Jiang, Jin-hong, Yin, Cui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468330/ https://www.ncbi.nlm.nih.gov/pubmed/31554960 http://dx.doi.org/10.1038/s41401-019-0299-4 |
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