WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice

The global prevalence of nonalcoholic steatohepatitis (NASH) increases incredibly. NASH ends up to advanced liver disease, which is highly threatening to human health. Currently, treatment of NASH is very limited. Acetyl-CoA carboxylases (ACC1/ACC2) are proved as effective drug targets for NASH. We...

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Detalles Bibliográficos
Autores principales: Gao, Ying-sheng, Qian, Min-yi, Wei, Qiang-qiang, Duan, Xu-bin, Wang, Shi-lei, Hu, Hai-yang, Liu, Jun, Pan, Chu-yue, Zhang, Shuo-quan, Qi, Lian-wen, Zhou, Jin-pei, Zhang, Hui-bin, Wang, Li-rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468331/
https://www.ncbi.nlm.nih.gov/pubmed/31645659
http://dx.doi.org/10.1038/s41401-019-0310-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468331/
https://www.ncbi.nlm.nih.gov/pubmed/31645659
http://dx.doi.org/10.1038/s41401-019-0310-0

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