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Rg1 improves LPS-induced Parkinsonian symptoms in mice via inhibition of NF-κB signaling and modulation of M1/M2 polarization

Ginsenoside Rg1 is one of the most active ingredients in ginseng, which has been reported to protect dopaminergic neurons and improve behavioral defects in MPTP model, 6-OHDA model and rotenone model. However, it is unclear whether Rg1 exerted neuroprotection in LPS-induced sub-acute PD model. In th...

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Detalles Bibliográficos
Autores principales: Liu, Jia-qi, Zhao, Ming, Zhang, Zhao, Cui, Li-yuan, Zhou, Xin, Zhang, Wei, Chu, Shi-feng, Zhang, Da-yong, Chen, Nai-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468333/
https://www.ncbi.nlm.nih.gov/pubmed/32203085
http://dx.doi.org/10.1038/s41401-020-0358-x