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Protective Effect of Croton macrostachyus (Euphorbiaceae) Stem Bark on Cyclophosphamide-Induced Nephrotoxicity in Rats

BACKGROUND: Cyclophosphamide is an alkylating antineoplastic agent and its major limitation is injury to normal tissue, leading to multiple organ toxicity, including kidney, heart, liver and reproductive toxicity. Croton macrostachyus (Euphorbiaceae) has been used in Ethiopian traditional medicine t...

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Detalles Bibliográficos
Autores principales: Ayza, Muluken Altaye, Rajkapoor, Balasubramanian, Wondafrash, Dawit Zewdu, Berhe, Abera Hadgu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468371/
https://www.ncbi.nlm.nih.gov/pubmed/32943947
http://dx.doi.org/10.2147/JEP.S260731