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Novel Therapeutic Approaches for the Treatment of Retinal Degenerative Diseases: Focus on CRISPR/Cas-Based Gene Editing

Inherited retinal diseases encompass a highly heterogenous group of disorders caused by a wide range of genetic variants and with diverse clinical symptoms that converge in the common trait of retinal degeneration. Indeed, mutations in over 270 genes have been associated with some form of retinal de...

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Detalles Bibliográficos
Autores principales: Gallego, Carmen, Gonçalves, Manuel A. F. V., Wijnholds, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468381/
https://www.ncbi.nlm.nih.gov/pubmed/32973430
http://dx.doi.org/10.3389/fnins.2020.00838