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The Use of Induced Pluripotent Stem Cells as a Model for Developmental Eye Disorders
Approximately one-third of childhood blindness is attributed to developmental eye disorders, of which 80% have a genetic cause. Eye morphogenesis is tightly regulated by a highly conserved network of transcription factors when disrupted by genetic mutations can result in severe ocular malformation....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468397/ https://www.ncbi.nlm.nih.gov/pubmed/32973457 http://dx.doi.org/10.3389/fncel.2020.00265 |