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Antagonism of CGRP Signaling by Rimegepant at Two Receptors

The “gepants” are a class of calcitonin gene-related peptide (CGRP) receptor antagonist molecules that have been developed for the prevention and treatment of migraine. Rimegepant is reported to act at the CGRP receptor, has good oral bioavailability, and has had positive clinical trial results. How...

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Detalles Bibliográficos
Autores principales: Pan, Kylie S., Siow, Andrew, Hay, Debbie L., Walker, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468408/
https://www.ncbi.nlm.nih.gov/pubmed/32973499
http://dx.doi.org/10.3389/fphar.2020.01240