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High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis
Cellular senescence is an irreversible cell growth arrest and is associated with aging and age-related diseases. High plasma phosphate (Pi) and deficiency of Klotho contribute to aging and kidney fibrosis, a pathological feature in the aging kidney and chronic kidney disease. This study examined the...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468469/ https://www.ncbi.nlm.nih.gov/pubmed/32973510 http://dx.doi.org/10.3389/fphar.2020.01273 |