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Mechanism-Driven Metabolic Engineering for Bio-Based Production of Free R-Lipoic Acid in Saccharomyces cerevisiae Mitochondria

Lipoic acid is a valuable organosulfur compound used as an antioxidant for dietary supplementation, and potentially anti-diabetic and anti-cancer. Currently, lipoic acid is obtained mainly through chemical synthesis, which requires toxic reagents and organic solvents, thus causing environmental issu...

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Detalles Bibliográficos
Autores principales: Chen, Binbin, Foo, Jee Loon, Ling, Hua, Chang, Matthew Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468506/
https://www.ncbi.nlm.nih.gov/pubmed/32974306
http://dx.doi.org/10.3389/fbioe.2020.00965