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Phagolysosomal Survival Enables Non-lytic Hyphal Escape and Ramification Through Lung Epithelium During Aspergillus fumigatus Infection

Aspergillus fumigatus is the most important mould pathogen in immunosuppressed patients. Suboptimal clearance of inhaled spores results in the colonisation of the lung airways by invasive hyphae. The first point of contact between A. fumigatus and the host is the lung epithelium. In vitro and ex viv...

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Detalles Bibliográficos
Autores principales: Seidel, Constanze, Moreno-Velásquez, Sergio D., Ben-Ghazzi, Nagwa, Gago, Sara, Read, Nick D., Bowyer, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468521/
https://www.ncbi.nlm.nih.gov/pubmed/32973709
http://dx.doi.org/10.3389/fmicb.2020.01955