Integrative Genomic Analysis Reveals Cancer-Associated Gene Mutations in Chronic Myeloid Leukemia Patients with Resistance or Intolerance to Tyrosine Kinase Inhibitor

INTRODUCTION: While the acquisition of mutations in the ABL1 kinase domain (KD) has been identified as a common mechanism behind tyrosine kinase inhibitor (TKI) resistance, recent genetic studies have revealed that patients with TKI resistance or intolerance frequently harbor one or more genetic alt...

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Detalles Bibliográficos
Autores principales: Wu, Waner, Xu, Na, Zhou, Xuan, Liu, Liang, Tan, Yaxian, Luo, Jie, Huang, Jixian, Qin, Jiayue, Wang, Juan, Li, Zhimin, Yin, Changxin, Zhou, Lingling, Liu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468532/
https://www.ncbi.nlm.nih.gov/pubmed/32943879
http://dx.doi.org/10.2147/OTT.S257661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468532/
https://www.ncbi.nlm.nih.gov/pubmed/32943879
http://dx.doi.org/10.2147/OTT.S257661

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