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Kanglexin, a novel anthraquinone compound, protects against myocardial ischemic injury in mice by suppressing NLRP3 and pyroptosis

Pyroptosis is a form of inflammatory cell death that could be driven by the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation following myocardial infarction (MI). Emerging evidence suggests the therapeutic potential for ameliora...

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Detalles Bibliográficos
Autores principales: Bian, Yu, Li, Xin, Pang, Ping, Hu, Xue-ling, Yu, Shu-ting, Liu, Yi-ning, Wang, Ning, Wang, Jin-hui, Xiao, Wei, Du, Wei-jie, Yang, Bao-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468574/
https://www.ncbi.nlm.nih.gov/pubmed/31645662
http://dx.doi.org/10.1038/s41401-019-0307-8