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Kanglexin, a novel anthraquinone compound, protects against myocardial ischemic injury in mice by suppressing NLRP3 and pyroptosis
Pyroptosis is a form of inflammatory cell death that could be driven by the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation following myocardial infarction (MI). Emerging evidence suggests the therapeutic potential for ameliora...
Autores principales: | Bian, Yu, Li, Xin, Pang, Ping, Hu, Xue-ling, Yu, Shu-ting, Liu, Yi-ning, Wang, Ning, Wang, Jin-hui, Xiao, Wei, Du, Wei-jie, Yang, Bao-feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468574/ https://www.ncbi.nlm.nih.gov/pubmed/31645662 http://dx.doi.org/10.1038/s41401-019-0307-8 |
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