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Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters

Quercetin is a flavonoid, its glycosides and aglycone are found in significant amounts in several plants and dietary supplements. Because of the high presystemic biotransformation of quercetin, mainly its conjugates appear in circulation. As has been reported in previous studies, quercetin can inter...

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Detalles Bibliográficos
Autores principales: Mohos, Violetta, Fliszár-Nyúl, Eszter, Ungvári, Orsolya, Kuffa, Katalin, Needs, Paul W., Kroon, Paul A., Telbisz, Ágnes, Özvegy-Laczka, Csilla, Poór, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468908/
https://www.ncbi.nlm.nih.gov/pubmed/32751996
http://dx.doi.org/10.3390/nu12082306