Cargando…

The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study

Extra virgin olive oil (EVOO) is suggested to be cardioprotective, partly due to its high phenolic content. We investigated the effect of extra virgin high polyphenol olive oil (HPOO) versus low polyphenol olive oil (LPOO) on blood pressure (BP) and arterial stiffness in healthy Australian adults. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarapis, Katerina, Thomas, Colleen J., Hoskin, Johanna, George, Elena S., Marx, Wolfgang, Mayr, Hannah L., Kennedy, Greg, Pipingas, Andrew, Willcox, Jane C., Prendergast, Luke A., Itsiopoulos, Catherine, Moschonis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468912/
https://www.ncbi.nlm.nih.gov/pubmed/32751219
http://dx.doi.org/10.3390/nu12082272
_version_ 1783578313596338176
author Sarapis, Katerina
Thomas, Colleen J.
Hoskin, Johanna
George, Elena S.
Marx, Wolfgang
Mayr, Hannah L.
Kennedy, Greg
Pipingas, Andrew
Willcox, Jane C.
Prendergast, Luke A.
Itsiopoulos, Catherine
Moschonis, George
author_facet Sarapis, Katerina
Thomas, Colleen J.
Hoskin, Johanna
George, Elena S.
Marx, Wolfgang
Mayr, Hannah L.
Kennedy, Greg
Pipingas, Andrew
Willcox, Jane C.
Prendergast, Luke A.
Itsiopoulos, Catherine
Moschonis, George
author_sort Sarapis, Katerina
collection PubMed
description Extra virgin olive oil (EVOO) is suggested to be cardioprotective, partly due to its high phenolic content. We investigated the effect of extra virgin high polyphenol olive oil (HPOO) versus low polyphenol olive oil (LPOO) on blood pressure (BP) and arterial stiffness in healthy Australian adults. In a double-blind, randomized, controlled cross-over trial, 50 participants (age 38.5 ± 13.9 years, 66% female) were randomized to consume 60 mL/day of either HPOO (360 mg/kg polyphenols) or LPOO (86 mg/kg polyphenols) for three weeks. Following a two-week washout period, participants crossed over to consume the alternate oil. Anthropometric data, peripheral BP, central BP and arterial stiffness were measured at baseline and follow up. No significant differences were observed in the changes from baseline to follow up between the two treatments. However, a significant decrease in peripheral and central systolic BP (SBP) by 2.5 mmHg (95% CI: −4.7 to −0.3) and 2.7 mmHg (95% CI: −4.7 to −0.6), respectively, was observed after HPOO consumption. Neither olive oil changed diastolic BP (DBP) or measures of arterial stiffness. The reductions in SBP after HPOO consumption provide evidence for a potentially widely accessible dietary intervention to prevent cardiovascular disease in a multiethnic population. Longer intervention studies and/or higher doses of EVOO polyphenols are warranted to elucidate the potential effect on DBP and arterial stiffness.
format Online
Article
Text
id pubmed-7468912
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-74689122020-09-04 The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study Sarapis, Katerina Thomas, Colleen J. Hoskin, Johanna George, Elena S. Marx, Wolfgang Mayr, Hannah L. Kennedy, Greg Pipingas, Andrew Willcox, Jane C. Prendergast, Luke A. Itsiopoulos, Catherine Moschonis, George Nutrients Article Extra virgin olive oil (EVOO) is suggested to be cardioprotective, partly due to its high phenolic content. We investigated the effect of extra virgin high polyphenol olive oil (HPOO) versus low polyphenol olive oil (LPOO) on blood pressure (BP) and arterial stiffness in healthy Australian adults. In a double-blind, randomized, controlled cross-over trial, 50 participants (age 38.5 ± 13.9 years, 66% female) were randomized to consume 60 mL/day of either HPOO (360 mg/kg polyphenols) or LPOO (86 mg/kg polyphenols) for three weeks. Following a two-week washout period, participants crossed over to consume the alternate oil. Anthropometric data, peripheral BP, central BP and arterial stiffness were measured at baseline and follow up. No significant differences were observed in the changes from baseline to follow up between the two treatments. However, a significant decrease in peripheral and central systolic BP (SBP) by 2.5 mmHg (95% CI: −4.7 to −0.3) and 2.7 mmHg (95% CI: −4.7 to −0.6), respectively, was observed after HPOO consumption. Neither olive oil changed diastolic BP (DBP) or measures of arterial stiffness. The reductions in SBP after HPOO consumption provide evidence for a potentially widely accessible dietary intervention to prevent cardiovascular disease in a multiethnic population. Longer intervention studies and/or higher doses of EVOO polyphenols are warranted to elucidate the potential effect on DBP and arterial stiffness. MDPI 2020-07-29 /pmc/articles/PMC7468912/ /pubmed/32751219 http://dx.doi.org/10.3390/nu12082272 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sarapis, Katerina
Thomas, Colleen J.
Hoskin, Johanna
George, Elena S.
Marx, Wolfgang
Mayr, Hannah L.
Kennedy, Greg
Pipingas, Andrew
Willcox, Jane C.
Prendergast, Luke A.
Itsiopoulos, Catherine
Moschonis, George
The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study
title The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study
title_full The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study
title_fullStr The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study
title_full_unstemmed The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study
title_short The Effect of High Polyphenol Extra Virgin Olive Oil on Blood Pressure and Arterial Stiffness in Healthy Australian Adults: A Randomized, Controlled, Cross-Over Study
title_sort effect of high polyphenol extra virgin olive oil on blood pressure and arterial stiffness in healthy australian adults: a randomized, controlled, cross-over study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468912/
https://www.ncbi.nlm.nih.gov/pubmed/32751219
http://dx.doi.org/10.3390/nu12082272
work_keys_str_mv AT sarapiskaterina theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT thomascolleenj theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT hoskinjohanna theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT georgeelenas theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT marxwolfgang theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT mayrhannahl theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT kennedygreg theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT pipingasandrew theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT willcoxjanec theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT prendergastlukea theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT itsiopouloscatherine theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT moschonisgeorge theeffectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT sarapiskaterina effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT thomascolleenj effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT hoskinjohanna effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT georgeelenas effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT marxwolfgang effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT mayrhannahl effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT kennedygreg effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT pipingasandrew effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT willcoxjanec effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT prendergastlukea effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT itsiopouloscatherine effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy
AT moschonisgeorge effectofhighpolyphenolextravirginoliveoilonbloodpressureandarterialstiffnessinhealthyaustralianadultsarandomizedcontrolledcrossoverstudy