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Untangling the origin and function of granulovacuolar degeneration bodies in neurodegenerative proteinopathies

In the brains of tauopathy patients, tau pathology coincides with the presence of granulovacuolar degeneration bodies (GVBs) both at the regional and cellular level. Recently, it was shown that intracellular tau pathology causes GVB formation in experimental models thus explaining the strong correla...

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Detalles Bibliográficos
Autores principales: Wiersma, Vera I., Hoozemans, Jeroen J. M., Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469111/
https://www.ncbi.nlm.nih.gov/pubmed/32883341
http://dx.doi.org/10.1186/s40478-020-00996-5