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LncRNA KCNQ1OT1 affects cell proliferation, apoptosis and fibrosis through regulating miR-18b-5p/SORBS2 axis and NF-ĸB pathway in diabetic nephropathy

BACKGROUND: It has been reported that long non-coding RNAs (lncRNAs) play vital roles in diabetic nephropathy (DN). Our study aims to research the function of lncRNA KCNQ1OT1 in DN cells and the molecular mechanism. METHODS: Human glomerular mesangial cells (HGMCs) and human renal glomerular endothe...

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Detalles Bibliográficos
Autores principales: Jie, Ran, Zhu, Pengpeng, Zhong, Jiao, Zhang, Yan, Wu, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469295/
https://www.ncbi.nlm.nih.gov/pubmed/32905431
http://dx.doi.org/10.1186/s13098-020-00585-5