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LncRNA KCNQ1OT1 affects cell proliferation, apoptosis and fibrosis through regulating miR-18b-5p/SORBS2 axis and NF-ĸB pathway in diabetic nephropathy
BACKGROUND: It has been reported that long non-coding RNAs (lncRNAs) play vital roles in diabetic nephropathy (DN). Our study aims to research the function of lncRNA KCNQ1OT1 in DN cells and the molecular mechanism. METHODS: Human glomerular mesangial cells (HGMCs) and human renal glomerular endothe...
Autores principales: | Jie, Ran, Zhu, Pengpeng, Zhong, Jiao, Zhang, Yan, Wu, Hongyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469295/ https://www.ncbi.nlm.nih.gov/pubmed/32905431 http://dx.doi.org/10.1186/s13098-020-00585-5 |
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