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ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals

BACKGROUND: Immunologic aging leads to immune dysfunction, significantly reducing the quality of life of the elderly. Aged-related defects in early hematopoiesis result in reduced lymphoid cell development, functionally defective mature immune cells, and poor protective responses to vaccines and pat...

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Detalles Bibliográficos
Autores principales: Ratliff, Michelle L., Garton, Joshua, James, Judith A., Webb, Carol F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469297/
https://www.ncbi.nlm.nih.gov/pubmed/32905435
http://dx.doi.org/10.1186/s12979-020-00198-6