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ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals
BACKGROUND: Immunologic aging leads to immune dysfunction, significantly reducing the quality of life of the elderly. Aged-related defects in early hematopoiesis result in reduced lymphoid cell development, functionally defective mature immune cells, and poor protective responses to vaccines and pat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469297/ https://www.ncbi.nlm.nih.gov/pubmed/32905435 http://dx.doi.org/10.1186/s12979-020-00198-6 |