Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

BACKGROUND: Emphysema is a crucial pathological characteristic of chronic obstructive pulmonary disease (COPD). Oxidative stress, apoptosis and epigenetic mechanisms contribute to the pathogenesis of emphysema. However, an attempt to accurately identify whether these mechanisms interact with each ot...

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Detalles Bibliográficos
Autores principales: Zeng, Huihui, Li, Tiao, He, Xue, Cai, Shan, Luo, Hong, Chen, Ping, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469342/
https://www.ncbi.nlm.nih.gov/pubmed/32883320
http://dx.doi.org/10.1186/s12931-020-01495-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469342/
https://www.ncbi.nlm.nih.gov/pubmed/32883320
http://dx.doi.org/10.1186/s12931-020-01495-w

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