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Utility of ultra-sensitive qPCR to detect Plasmodium falciparum and Plasmodium vivax infections under different transmission intensities

BACKGROUND: The use of molecular diagnostics has revealed an unexpectedly large number of asymptomatic low-density malaria infections in many malaria endemic areas. This study compared the gains in parasite prevalence obtained by the use of ultra-sensitive (us)-qPCR as compared to standard qPCR in c...

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Detalles Bibliográficos
Autores principales: Gruenberg, Maria, Moniz, Clara Antunes, Hofmann, Natalie E., Koepfli, Cristian, Robinson, Leanne J., Nate, Elma, Monteiro, Wuelton Marcelo, de Melo, Gisely Cardoso, Kuehn, Andrea, Siqueira, Andre M., Nguitragool, Wang, Bassat, Quique, Lacerda, Marcus, Sattabongkot, Jetsumon, Mueller, Ivo, Felger, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469345/
https://www.ncbi.nlm.nih.gov/pubmed/32883308
http://dx.doi.org/10.1186/s12936-020-03374-7