Discovery of Harmaline as a Potent Inhibitor of Sphingosine Kinase-1: A Chemopreventive Role in Lung Cancer

[Image: see text] The sphingosine kinase-1/sphingosine-1-phosphate pathway is linked with the cancer progression and survival of the chemotherapy-challenged cells. Sphingosine kinase-1 (SphK1) has emerged as an attractive drug target, but their inhibitors from natural sources are limited. In this st...

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Detalles Bibliográficos
Autores principales: Roy, Sonam, Mohammad, Taj, Gupta, Preeti, Dahiya, Rashmi, Parveen, Shahnaz, Luqman, Suaib, Hasan, Gulam Mustafa, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469376/
https://www.ncbi.nlm.nih.gov/pubmed/32905276
http://dx.doi.org/10.1021/acsomega.0c02165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469376/
https://www.ncbi.nlm.nih.gov/pubmed/32905276
http://dx.doi.org/10.1021/acsomega.0c02165

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