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Conformation and Morphology of 4-(NH(2)/OH)-Substituted l/d-Prolyl Polypeptides: Effect of Homo- and Heterochiral Backbones on Formation of β-Structures and Nanofibers
[Image: see text] The relative stereochemistry of C2 and C4 in 4-substituted prolyl polypeptides plays an important role in defining the derived conformation in solution. cis-(2S,4S)-Amino/hydroxy-l-prolyl polypeptide (l(C)-Amp(9)/l(C)-Hyp(9)) shows a PPII conformation in phosphate buffer and a β-st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469381/ https://www.ncbi.nlm.nih.gov/pubmed/32905392 http://dx.doi.org/10.1021/acsomega.0c02826 |