Conformation and Morphology of 4-(NH(2)/OH)-Substituted l/d-Prolyl Polypeptides: Effect of Homo- and Heterochiral Backbones on Formation of β-Structures and Nanofibers

[Image: see text] The relative stereochemistry of C2 and C4 in 4-substituted prolyl polypeptides plays an important role in defining the derived conformation in solution. cis-(2S,4S)-Amino/hydroxy-l-prolyl polypeptide (l(C)-Amp(9)/l(C)-Hyp(9)) shows a PPII conformation in phosphate buffer and a β-st...

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Detalles Bibliográficos
Autores principales: Madhanagopal, Bharath Raj, More, Shahaji H., Bansode, Nitin D., Ganesh, Krishna N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469381/
https://www.ncbi.nlm.nih.gov/pubmed/32905392
http://dx.doi.org/10.1021/acsomega.0c02826

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