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NORRIN plays a context-dependent role in glioblastoma stem cells

We recently reported a novel role of the atypical Wnt ligand, NORRIN, in mediating the proliferation and stemness of glioblastoma stem cells. Mechanistic and functional analysis revealed context-specific phenotypes in which NORRIN can induce opposite effects on the tumor outcome, depending on the un...

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Detalles Bibliográficos
Autores principales: El-Sehemy, Ahmed, Wallace, Valerie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469435/
https://www.ncbi.nlm.nih.gov/pubmed/32944619
http://dx.doi.org/10.1080/23723556.2020.1758540