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In vitro characterization of the effects of chronic insulin stimulation in mouse 3T3-L1 and human SGBS adipocytes

Hyperinsulinemia is the hallmark of the development of insulin resistance and precedes the diagnosis of type 2 diabetes. Here we evaluated the effects of prolonged exposure (≥4 days) to high insulin doses (150 nM) in vitro in two adipose cell types, mouse 3T3-L1 and human SGBS. Chronic insulin treat...

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Detalles Bibliográficos
Autores principales: Rossi, A., Eid, M., Dodgson, J., Davies, G., Musial, B., Wabitsch, M., Church, C., Hornigold, D.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469436/
https://www.ncbi.nlm.nih.gov/pubmed/32718202
http://dx.doi.org/10.1080/21623945.2020.1798613