Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation

Adipocyte-mediated inflammatory signalling has been proposed to alter adipose physiology in obesity and Type 2 diabetes mellitus. Novel targets for alteration of inflammatory signalling are needed to improve obesity-related outcomes. The γ-secretase enzyme complex has been suggested to play a role b...

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Detalles Bibliográficos
Autores principales: Sparling, David P., McCullough, Nile, Pajvani, Utpal, Humphrey, Mary Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469479/
https://www.ncbi.nlm.nih.gov/pubmed/32603641
http://dx.doi.org/10.1080/21623945.2020.1788235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469479/
https://www.ncbi.nlm.nih.gov/pubmed/32603641
http://dx.doi.org/10.1080/21623945.2020.1788235

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