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Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation
Adipocyte-mediated inflammatory signalling has been proposed to alter adipose physiology in obesity and Type 2 diabetes mellitus. Novel targets for alteration of inflammatory signalling are needed to improve obesity-related outcomes. The γ-secretase enzyme complex has been suggested to play a role b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469479/ https://www.ncbi.nlm.nih.gov/pubmed/32603641 http://dx.doi.org/10.1080/21623945.2020.1788235 |