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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

Macroautophagy/autophagy can enable cancer cells to withstand cellular stress and maintain bioenergetic homeostasis by sequestering cellular components into newly formed double-membrane vesicles destined for lysosomal degradation, potentially affecting the efficacy of anti-cancer treatments. Using (...

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Detalles Bibliográficos
Autores principales: Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469489/
https://www.ncbi.nlm.nih.gov/pubmed/31517566
http://dx.doi.org/10.1080/15548627.2019.1659608