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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy
Macroautophagy/autophagy can enable cancer cells to withstand cellular stress and maintain bioenergetic homeostasis by sequestering cellular components into newly formed double-membrane vesicles destined for lysosomal degradation, potentially affecting the efficacy of anti-cancer treatments. Using (...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469489/ https://www.ncbi.nlm.nih.gov/pubmed/31517566 http://dx.doi.org/10.1080/15548627.2019.1659608 |