TDG is a novel tumor suppressor of liver malignancies

In a recent publication, we demonstrated that conditional deletion of the gene encoding thymine DNA glycosylase (TDG) leads to a late onset of hepatocellular carcinoma (HCC). TDG loss causes disruption in active DNA demethylation in the liver and dysregulation of the farnesoid X receptor and small h...

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Detalles Bibliográficos
Autores principales: Hassan, Haider M., Isovic, Majdina, Underhill, Michael Tully, Torchia, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469547/
https://www.ncbi.nlm.nih.gov/pubmed/32944627
http://dx.doi.org/10.1080/23723556.2020.1768819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469547/
https://www.ncbi.nlm.nih.gov/pubmed/32944627
http://dx.doi.org/10.1080/23723556.2020.1768819

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