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TDG is a novel tumor suppressor of liver malignancies
In a recent publication, we demonstrated that conditional deletion of the gene encoding thymine DNA glycosylase (TDG) leads to a late onset of hepatocellular carcinoma (HCC). TDG loss causes disruption in active DNA demethylation in the liver and dysregulation of the farnesoid X receptor and small h...
Autores principales: | Hassan, Haider M., Isovic, Majdina, Underhill, Michael Tully, Torchia, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469547/ https://www.ncbi.nlm.nih.gov/pubmed/32944627 http://dx.doi.org/10.1080/23723556.2020.1768819 |
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