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Cathepsin gene expression in abdominal subcutaneous adipose tissue of obese/overweight humans

Cathepsin L1 (CTSL1) and B (CTSB) are lysosomal proteases, of which the expression and activity are impaired in adipose tissue (AT) of obese rodents, indicating AT lysosomal dysfunction. Here we assess the relation between abdominal subcutaneous AT (SCAT) CTSL1 and CTSB gene expression (qRT-PCR), bo...

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Bibliographic Details
Main Authors: Xu, Qing, Mariman, Edwin C. M., Goossens, Gijs H., Blaak, Ellen E., Jocken, Johan W. E.
Format: Online Article Text
Language:English
Published: Taylor & Francis 2020
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469552/
https://www.ncbi.nlm.nih.gov/pubmed/32486882
http://dx.doi.org/10.1080/21623945.2020.1775035