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Cathepsin gene expression in abdominal subcutaneous adipose tissue of obese/overweight humans

Cathepsin L1 (CTSL1) and B (CTSB) are lysosomal proteases, of which the expression and activity are impaired in adipose tissue (AT) of obese rodents, indicating AT lysosomal dysfunction. Here we assess the relation between abdominal subcutaneous AT (SCAT) CTSL1 and CTSB gene expression (qRT-PCR), bo...

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Detalles Bibliográficos
Autores principales: Xu, Qing, Mariman, Edwin C. M., Goossens, Gijs H., Blaak, Ellen E., Jocken, Johan W. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469552/
https://www.ncbi.nlm.nih.gov/pubmed/32486882
http://dx.doi.org/10.1080/21623945.2020.1775035